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<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.1 20151215//EN" "https://jats.nlm.nih.gov/publishing/1.1/JATS-journalpublishing1.dtd">
<article article-type="research-article" dtd-version="1.1" specific-use="sps-1.9" xml:lang="en" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">Indian Journal of Mental Health and Neurosciences</journal-id>
<journal-id journal-id-type="publisher-id">IJMHNS</journal-id>
<journal-title-group>
<journal-title>Indian Journal of Mental Health and Neurosciences</journal-title>
<abbrev-journal-title abbrev-type="publisher">IJMHNS</abbrev-journal-title>
</journal-title-group>
<issn pub-type="epub">2581-9445</issn>
<publisher>
<publisher-name>Indian Psychiatric Society - Tamil Nadu</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.32746/ijmhns.2021.v4.i1.49</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Original Article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Phenomenology and Severity of Symptoms in OCD Patients After COVID 19: A Cohort Study</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Nandhini</surname>
<given-names>Usha</given-names>
</name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Vaishali</surname>
<given-names>S</given-names>
</name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Vedachalam</surname>
<given-names>Ahalya</given-names>
</name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Sudhakar</surname>
<given-names>S</given-names>
</name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Kannan</surname>
<given-names>PP</given-names>
</name>
<xref ref-type="aff" rid="aff3"><sup>3</sup></xref>
</contrib>
</contrib-group>
<aff id="aff1">
<label>1</label>
<institution content-type="original">Junior Resident, Department of Psychiatry, Chengalpattu medical college</institution>
<institution content-type="orgname">Junior Resident, Department of Psychiatry</institution>
<institution content-type="orgdiv1">Chengalpattu medical college</institution>
</aff>
<aff id="aff2">
<label>2</label>
<institution content-type="original">Assistant Professor, Department of Psychiatry, Chengalpattu Medical College,</institution>
<institution content-type="orgname">Assistant Professor, Department of Psychiatry</institution>
<institution content-type="orgdiv1">Chengalpattu Medical College</institution>
</aff>
<aff id="aff3">
<label>3</label>
<institution content-type="original">Professor of Psychiatry, Department of Psychiatry, Chengalpattu Medical College</institution>
<institution content-type="orgname">Professor of Psychiatry, Department of Psychiatry</institution>
<institution content-type="orgdiv1">Chengalpattu Medical College</institution>
</aff>
<author-notes>
<corresp id="c1"><bold>Address for Correspondence:</bold> Dr. Sudhakar. S, Assistant Professor, Department of Psychiatry, Government Chengalpattu Medical College, Chengalpattu, Tamilnadu, India. E-mail: <email>sudhakarpsychiatrist@yahoo.com</email></corresp>
<fn fn-type="other" id="fn1">
<p><bold>Running Title:</bold> Changes in OCD in COVID pandemic</p></fn>
<fn fn-type="edited-by" id="fn2">
<label>How to Cite this Article:</label>
<p>Nandhini U, Vaishali S, Vedachalam A, Sudhakar S, Kannan PP. Phenomenology and severity of symptoms in OCD patients after COVID 19: A cohort study: A case report. Indian Journal of Mental Health and Neurosciences. 2020;4(l): pp 18-22</p></fn>
</author-notes>
<pub-date date-type="pub" publication-format="electronic">
<day>04</day>
<month>09</month>
<year>2025</year>
</pub-date>
<pub-date date-type="collection" publication-format="electronic">
<year>2024</year>
</pub-date>
<volume>4</volume>
<issue>1</issue>
<fpage>18</fpage>
<lpage>22</lpage>
<history>
<date date-type="received">
<day>01</day>
<month>07</month>
<year>2024</year>
</date>
<date date-type="accepted">
<day>01</day>
<month>07</month>
<year>2024</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#x00A9; 2024 Indian Psychiatric Society &#x2014; Tamil Nadu Branch</copyright-statement>
<copyright-year>2024</copyright-year>
<copyright-holder>Indian Psychiatric Society &#x2014; Tamil Nadu Branch</copyright-holder>
<license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/" xml:lang="en">
<license-p>This is an open access article distributed under the terms of the Creative Commons license.</license-p>
</license>
</permissions>
<abstract>
<title>ABSTRACT</title>
<sec>
<title>Background:</title>
<p>COVID 19 pandemic and the associated restrictions can have significant impact on patients with pre-existing mental disorders. Fear of getting infected and excessive focus on contamination can worsen in patients with OCD.</p>
</sec>
<sec>
<title>Methodology:</title>
<p>Thirty patients with OCD attending Chengalpattu Medical College Hospital were evaluated for OCD symptom severity using Y-BOCS severity scores in June &#x0026; July 2020 and that was compared with their scores five months prior (pre covid)</p>
</sec>
<sec>
<title>Results:</title>
<p>Majority of the study population (53%) had no changes in symptom severity after the onset of COVID19 pandemic. Twenty seven percent (27%) had a decrease in symptom severity while only 20% had increase in severity.</p>
</sec>
<sec>
<title>Conclusion:</title>
<p>Our study results indicate that there were no significant changes in OCD symptom severity after the onset of COVID 19 pandemic.</p>
</sec>
</abstract>
<kwd-group xml:lang="en">
<title>Keywords:</title>
<kwd>OCD</kwd>
<kwd>COVID 19</kwd>
<kwd>Severity</kwd>
</kwd-group>
<counts>
<table-count count="4"/>
<ref-count count="11"/>
</counts>
</article-meta>
</front>
<body>
<sec sec-type="intro">
<title>INTRODUCTION</title>
<p>Obsessive&#x2013;compulsive disorder (OCD) is a neuropsychiatric disorder with prevalence of 1-3 % in general population.<sup><xref ref-type="bibr" rid="B1">1</xref></sup> OCD is characterized by recurrent obsessions, such as persistent thoughts, impulses or mental images, that promote anxiety, and uncontrolled compulsions such as repetitive behaviours or mental acts that are performed in response to the obsessions with the intent of reducing anxiety. Of the multiple symptom domains, obsessions of contamination and compulsive hand washing are amongst the commonest. These domains respond well to pharmacotherapy and psychotherapy, it tends to relapse in case of stress due to external or environmental cues.<sup><xref ref-type="bibr" rid="B2">2</xref></sup></p>
<p>Adam Abba et al,<sup><xref ref-type="bibr" rid="B3">3</xref></sup> reported that the prevalence of OCD symptoms increased during the early phase of the COVID-19 pandemic, at a rate significantly higher than pre-pandemic rates in the general population. Also, other studies have suggested that there could be significant worsening of (OCD) in the context of the current COVID-19 pandemic.<sup><xref ref-type="bibr" rid="B4">4</xref>,<xref ref-type="bibr" rid="B5">5</xref>,<xref ref-type="bibr" rid="B6">6</xref>,<xref ref-type="bibr" rid="B7">7</xref></sup> One study reported that psychoeducation of the patients and families, facilitating tele-consults and psychotherapy, enhancing medication compliance and social worker input potentially reduce the worsening of symptoms in this population.<sup><xref ref-type="bibr" rid="B5">5</xref></sup></p>
<p>Hence the aim of this study was to understand the impact of Covid-19 on the mental health of patients with OCD in an Indian setting and find out if there is a need to modify or intensify their treatment.</p>
</sec>
<sec sec-type="methods">
<title>METHODOLOGY</title>
<p>The study was conducted in the psychiatry department of Chengalpattu medical college and hospital in Tamilnadu. Thirty patients with OCD who were already a part of a previous study were reassessed for severity of OCD symptoms in June and July 2020. These scores were compared with that from the earlier assessment of severity done in January &#x0026; February 2020. The protocol was approved by the institute ethics committee and patients provided informed consent to be part of this study.</p>
<sec>
<title>Measures</title>
<p>Socio demographic and clinical profile was obtained using a semi structured proforma. The Y&#x2013;BOCS-SC was used to identify the content of the obsessions and compulsions8 and the Y-BOCS Severity Score, a 10- item instrument developed by Goodman et al was used to evaluate symptom severity and treatment response.8 The knowledge of patients about Covid-19 was assessed using semi-structured interview. This consisted of five questions regarding the mode of spread, symptoms of the illness, course of illness, treatment available and preventive measures SPSS software was used for statistical analysis. Descriptive statistics of socio demographic and clinical profile was used. Paired t &#x2013; test analysis was performed for comparison of mean scores of YBOCS before and during COVID 19.</p>
</sec>
</sec>
<sec>
<title>RESULTS:</title>
<sec>
<title>Socio demographic characteristics</title>
<p>In our sample 60 % [ n = 18] were male and 60% [ n = 18] were from rural background. 50 % [ n=15] had primary level of education. 60% [ n= 18] were employed and 73% [ n = 22] were married. <bold>(<xref ref-type="table" rid="T1">Table 1</xref>)</bold></p>
<table-wrap id="T1" position="float">
<label>Table 1</label>
<caption>
<title>Demographic details, (n=30)</title>
</caption>
<table cellpadding="5" cellspacing="5" frame="box" rules="all">
<thead>
<tr>
<th align="center" valign="middle">S No</th>
<th align="center" valign="middle" colspan="2">Variable</th>
<th align="center" valign="middle">Frequency</th>
<th align="center" valign="middle">Percentage</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top" rowspan="4">1</td>
<td align="left" valign="top" rowspan="4">Age</td>
<td valign="middle" align="left">20-30</td>
<td valign="middle" align="center">9</td>
<td valign="middle" align="center">30</td>
</tr>
<tr>
<td valign="middle" align="left">31-40</td>
<td valign="middle" align="center">9</td>
<td valign="middle" align="center">30</td>
</tr>
<tr>
<td valign="middle" align="left">41-50</td>
<td valign="middle" align="center">9</td>
<td valign="middle" align="center">30</td>
</tr>
<tr>
<td valign="middle" align="left">&#62;50</td>
<td valign="middle" align="center">3</td>
<td valign="middle" align="center">10</td>
</tr>
<tr>
<td align="left" valign="top" rowspan="2">2</td>
<td align="left" valign="top" rowspan="2">Gender</td>
<td valign="middle" align="left">Male</td>
<td valign="middle" align="center">18</td>
<td valign="middle" align="center">60</td>
</tr>
<tr>
<td valign="middle" align="left">Female</td>
<td valign="middle" align="center">12</td>
<td valign="middle" align="center">40</td>
</tr>
<tr>
<td align="left" valign="top" rowspan="3">3</td>
<td align="left" valign="top" rowspan="3">Locality</td>
<td valign="middle" align="left">Rural</td>
<td valign="middle" align="center">14</td>
<td valign="middle" align="center">47</td>
</tr>
<tr>
<td valign="middle" align="left">Semi urban</td>
<td valign="middle" align="center">8</td>
<td valign="middle" align="center">27</td>
</tr>
<tr>
<td valign="middle" align="left">Urban</td>
<td valign="middle" align="center">8</td>
<td valign="middle" align="center">27</td>
</tr>
<tr>
<td align="left" valign="top" rowspan="2">4</td>
<td align="left" valign="top" rowspan="2">SES</td>
<td valign="middle" align="left">Lower</td>
<td valign="middle" align="center">16</td>
<td valign="middle" align="center">53</td>
</tr>
<tr>
<td valign="middle" align="left">Middle</td>
<td valign="middle" align="center">14</td>
<td valign="middle" align="center">47</td>
</tr>
<tr>
<td align="left" valign="top" rowspan="4">5</td>
<td align="left" valign="top" rowspan="4">Education</td>
<td valign="middle" align="left">Illiterate</td>
<td valign="middle" align="center">1</td>
<td valign="middle" align="center">3</td>
</tr>
<tr>
<td valign="middle" align="left">Primary</td>
<td valign="middle" align="center">15</td>
<td valign="middle" align="center">50</td>
</tr>
<tr>
<td valign="middle" align="left">Secondary</td>
<td valign="middle" align="center">6</td>
<td valign="middle" align="center">20</td>
</tr>
<tr>
<td valign="middle" align="left">College</td>
<td valign="middle" align="center">8</td>
<td valign="middle" align="center">27</td>
</tr>
<tr>
<td align="left" valign="top" rowspan="4">6</td>
<td align="left" valign="top" rowspan="4">Employment</td>
<td valign="middle" align="left">Professional</td>
<td valign="middle" align="center">1</td>
<td valign="middle" align="center">3</td>
</tr>
<tr>
<td valign="middle" align="left">Skilled</td>
<td valign="middle" align="center">5</td>
<td valign="middle" align="center">17</td>
</tr>
<tr>
<td valign="middle" align="left">Semi skilled</td>
<td valign="middle" align="center">12</td>
<td valign="middle" align="center">40</td>
</tr>
<tr>
<td valign="middle" align="left">Unemployed</td>
<td valign="middle" align="center">12</td>
<td valign="middle" align="center">40</td>
</tr>
<tr>
<td align="left" valign="top" rowspan="3">7</td>
<td align="left" valign="top" rowspan="3">Marital status</td>
<td valign="middle" align="left">Married</td>
<td valign="middle" align="center">22</td>
<td valign="middle" align="center">73</td>
</tr>
<tr>
<td valign="middle" align="left">Unmarried</td>
<td valign="middle" align="center">7</td>
<td valign="middle" align="center">23</td>
</tr>
<tr>
<td valign="middle" align="left">Divorced</td>
<td valign="middle" align="center">1</td>
<td valign="middle" align="center">3</td>
</tr>
</tbody>
</table>
</table-wrap>
</sec>
<sec>
<title>Clinical Characteristics</title>
<p>Many had duration of illness greater than 5 years, 66 % [ n= 20]. About 10% [ n= 3] were drug naive and 50 % [ n= 15] were on regular treatment.23% [ n= 7] had a past history of suicide attempt. 20 % [ n= 6] had a family history of psychiatric illness and 43% [ n = 13] had alcohol use. <bold>(<xref ref-type="table" rid="T2">Table 2</xref>)</bold></p>
<table-wrap id="T2" position="float">
<label>Table 2</label>
<caption>
<title>Clinical characteristics of the sample</title>
</caption>
<table cellpadding="5" cellspacing="5" frame="box" rules="all">
<thead>
<tr>
<th align="center" valign="middle">S No.</th>
<th align="center" valign="middle" colspan="2">Variable</th>
<th align="center" valign="middle">Frequency</th>
<th align="center" valign="middle">Percentage</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top" rowspan="3">1</td>
<td align="left" valign="top" rowspan="3">Duration of illness</td>
<td valign="middle" align="left">&#60;5 years</td>
<td valign="middle" align="center">10</td>
<td valign="middle" align="center">33</td>
</tr>
<tr>
<td valign="middle" align="left">5-10 years</td>
<td valign="middle" align="center">16</td>
<td valign="middle" align="center">53</td>
</tr>
<tr>
<td valign="middle" align="left">&#62;10 years</td>
<td valign="middle" align="center">4</td>
<td valign="middle" align="center">13</td>
</tr>
<tr>
<td align="left" valign="top" rowspan="3">2</td>
<td align="left" valign="top" rowspan="3">Treatment history</td>
<td valign="middle" align="left">Regular</td>
<td valign="middle" align="center">15</td>
<td valign="middle" align="center">50</td>
</tr>
<tr>
<td valign="middle" align="left">Irregular</td>
<td valign="middle" align="center">12</td>
<td valign="middle" align="center">40</td>
</tr>
<tr>
<td valign="middle" align="left">Drug naive</td>
<td valign="middle" align="center">3</td>
<td valign="middle" align="center">10</td>
</tr>
<tr>
<td align="left" valign="top" rowspan="3">3</td>
<td align="left" valign="top" rowspan="3">Past history</td>
<td valign="middle" align="left">Seizure disorder</td>
<td valign="middle" align="center">2</td>
<td valign="middle" align="center">7</td>
</tr>
<tr>
<td valign="middle" align="left">Suicide attempt</td>
<td valign="middle" align="center">7</td>
<td valign="middle" align="center">23</td>
</tr>
<tr>
<td valign="middle" align="left">Nil</td>
<td valign="middle" align="center">21</td>
<td valign="middle" align="center">70</td>
</tr>
<tr>
<td align="left" valign="top" rowspan="2">4</td>
<td align="left" valign="top" rowspan="2">Family history</td>
<td valign="middle" align="left">No</td>
<td valign="middle" align="center">24</td>
<td valign="middle" align="center">80</td>
</tr>
<tr>
<td valign="middle" align="left">Yes</td>
<td valign="middle" align="center">6</td>
<td valign="middle" align="center">20</td>
</tr>
<tr>
<td align="left" valign="top" rowspan="4">5</td>
<td align="left" valign="top" rowspan="4">Substance use</td>
<td valign="middle" align="left">Alcohol</td>
<td valign="middle" align="center">13</td>
<td valign="middle" align="center">43</td>
</tr>
<tr>
<td valign="middle" align="left">Alcohol and Tobacco</td>
<td valign="middle" align="center">1</td>
<td valign="middle" align="center">3</td>
</tr>
<tr>
<td valign="middle" align="left">Tobacco</td>
<td valign="middle" align="center">1</td>
<td valign="middle" align="center">3</td>
</tr>
<tr>
<td valign="middle" align="left">Nil</td>
<td valign="middle" align="center">15</td>
<td valign="middle" align="center">50</td>
</tr>
</tbody>
</table>
</table-wrap>
</sec>
<sec>
<title>Profile of OCD in the sample</title>
<p>Obsesions on themes of contamination, aggression was most common. Cleaning and checking compulsions were the most frequent. The different types of obsessions and compulsions seen and their frequency of occurrence in this study population is noted.<bold>(<xref ref-type="table" rid="T3">Table 3</xref>)</bold></p>
<table-wrap id="T3" position="float">
<label>Table 3</label>
<caption>
<title>Frequency of obsessions and compulsions by domain</title>
</caption>
<table cellpadding="5" cellspacing="5" frame="box" rules="all">
<thead>
<tr>
<th align="center" valign="middle">S No.</th>
<th align="center" valign="middle">Obsessions</th>
<th align="center" valign="middle">Frequency</th>
<th align="center" valign="middle">Percent</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="middle" align="left">1</td>
<td valign="middle" align="left">Aggressive</td>
<td valign="middle" align="center">9</td>
<td valign="middle" align="center">23%</td>
</tr>
<tr>
<td valign="middle" align="left">2</td>
<td valign="middle" align="left">Contamination</td>
<td valign="middle" align="center">9</td>
<td valign="middle" align="center">23%</td>
</tr>
<tr>
<td valign="middle" align="left">3</td>
<td valign="middle" align="left">Somatic</td>
<td valign="middle" align="center">4</td>
<td valign="middle" align="center">10%</td>
</tr>
<tr>
<td valign="middle" align="left">4</td>
<td valign="middle" align="left">Religious</td>
<td valign="middle" align="center">3</td>
<td valign="middle" align="center">8%</td>
</tr>
<tr>
<td valign="middle" align="left">5</td>
<td valign="middle" align="left">Sexual</td>
<td valign="middle" align="center">8</td>
<td valign="middle" align="center">21%</td>
</tr>
<tr>
<td valign="middle" align="left">6</td>
<td valign="middle" align="left">Miscellaneous</td>
<td valign="middle" align="center">2</td>
<td valign="middle" align="center">5%</td>
</tr>
<tr>
<td valign="middle" align="left">7</td>
<td valign="middle" align="left">Symmetry</td>
<td valign="middle" align="center">2</td>
<td valign="middle" align="center">5%</td>
</tr>
<tr>
<td valign="middle" align="left">8</td>
<td valign="middle" align="left">Nil</td>
<td valign="middle" align="center">2</td>
<td valign="middle" align="center">5%</td>
</tr>
<tr>
<td valign="middle" align="center"><bold>S No.</bold></td>
<td valign="middle" align="center"><bold>Compulsions</bold></td>
<td valign="middle" align="center"><bold>Frequency</bold></td>
<td valign="middle" align="center"><bold>Percent</bold></td>
</tr>
<tr>
<td valign="middle" align="left">1</td>
<td valign="middle" align="left">Cleaning</td>
<td valign="middle" align="center">17</td>
<td valign="middle" align="center">36%</td>
</tr>
<tr>
<td valign="middle" align="left">2</td>
<td valign="middle" align="left">Checking</td>
<td valign="middle" align="center">13</td>
<td valign="middle" align="center">28%</td>
</tr>
<tr>
<td valign="middle" align="left">3</td>
<td valign="middle" align="left">Miscellaneous</td>
<td valign="middle" align="center">5</td>
<td valign="middle" align="center">11%</td>
</tr>
<tr>
<td valign="middle" align="left">4</td>
<td valign="middle" align="left">Repeating rituals</td>
<td valign="middle" align="center">4</td>
<td valign="middle" align="center">9%</td>
</tr>
<tr>
<td valign="middle" align="left">5</td>
<td valign="middle" align="left">No compulsions</td>
<td valign="middle" align="center">8</td>
<td valign="middle" align="center">17%</td>
</tr>
</tbody>
</table>
</table-wrap>
</sec>
<sec>
<title>Changes in severity of symptoms after COVID 19</title>
<p>We found that about 20 % [ n= 6] of the patients had increase in the severity of symptoms following COVID 19 while 27% [ n = 8] of the patients had decrease in the severity of symptoms and 53% [ n = 16] of the patients had no changes in the severity of symptoms following COVID 19.Paired samples t-test showed there was no significant difference (p value- 0.202) in the Y BOCS score before (16.04) and after pandemic (15.03).<bold>(<xref ref-type="table" rid="T4">Table 4</xref>)</bold></p>
<table-wrap id="T4" position="float">
<label>Table 4</label>
<caption>
<title>Change in severity of symptoms after COVID 19</title>
</caption>
<table cellpadding="5" cellspacing="5" frame="box" rules="all">
<thead>
<tr>
<th align="center" valign="middle">Change in severity</th>
<th align="center" valign="middle">Frequency</th>
<th align="center" valign="middle">Percentage</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="middle" align="left">Increased</td>
<td valign="middle" align="center">6</td>
<td valign="middle" align="center">20%</td>
</tr>
<tr>
<td valign="middle" align="left">Decreased</td>
<td valign="middle" align="center">8</td>
<td valign="middle" align="center">27%</td>
</tr>
<tr>
<td valign="middle" align="left">No changes</td>
<td valign="middle" align="center">16</td>
<td valign="middle" align="center">53%</td>
</tr>
<tr>
<td valign="middle" align="left">&#8195;<bold>Change in YBOCS</bold></td>
<td valign="middle" align="center"><bold>Mean Score</bold></td>
<td valign="middle" align="center"><bold>p value</bold></td>
</tr>
<tr>
<td valign="middle" align="left">Pre Pandemic</td>
<td valign="middle" align="center">16.04</td>
<td valign="middle" rowspan="2" align="center">0.202</td>
</tr>
<tr>
<td valign="middle" align="left">Post Pandemic</td>
<td valign="middle" align="center">15.03</td>
</tr>
</tbody>
</table>
</table-wrap>

</sec>
</sec>
<sec sec-type="discussion">
<title>DISCUSSION</title>
<p>The spread of fear, anxiety and even panic due to the COVID-19 pandemic can lead to a worsening of preexisting psychiatric disorders (Yao et al., 2020).<sup><xref ref-type="bibr" rid="B9">9</xref></sup> There are few studies in India regarding the changes in OCD symptoms following COVID 19.</p>
<p>In our sample of 30 patients only 20% of the patients had increase in the severity of symptoms following COVID 19. As a whole group, there was no significant differences in severity of symptoms before and after the onset of COVID 19. This is different to the findings of another studies by Davide et al, of 30 patients, where they found that there was overall worsening of symptoms.<sup><xref ref-type="bibr" rid="B1">10</xref></sup> That study included only patients with contamination symptoms whereas, in this sample patients with all subtypes were included. The mean YBOCS score before the COVID 19 was 15. 97 which is like our sample score 16. 04. The mean YBOCS score during pandemic was 20. 6 in their sample which is higher than in our sample which was 15.03.</p>
<p>In a cross-sectional study conducted by Benatti et al, 36% of the patients had clinical worsening of symptoms which is little higher than our sample were only 20% had worsening of symptoms. 39 % were employed in their study which is contradictory to our sample were 60 % were employed. Most common obsession was aggressive type and compulsions were cleaning type which is similar to our sample.<sup><xref ref-type="bibr" rid="B11">11</xref></sup></p>
<p>There could be a few reasons why there was no significant worsening in the study sample. The clients with OCD in this study were continuing their treatment for a longer duration (majority with an illness duration of more than five years). They might represent a group with better understanding of their condition, significant clinical improvement, resilience and better ability to deal with the challenges posed by the pandemic. Most of the patients were on regular follow up and treatment even during the lockdown and for those who couldn&#x2019;t reach the hospital, tele-therapy was started and based on the symptoms patients were advised to get drugs from nearby hospitals.</p>
</sec>
<sec>
<title>LIMITATIONS</title>
<p>Our study had a small sample size from a tertiary care hospital and results cannot be generalized. There is high risk of selection bias as those who follow up regularly might be a group with better prognosis. Half of the patients in our sample had mild to moderate severity, so the impact on those with severe illness could be underestimated.</p>
</sec>
<sec>
<title>CONCLUSION AND FUTURE DIRECTIONS</title>
<p>The effects of pandemic on the mental health in OCD patients might be variable. It is necessary that the patients to be in regular follow up and treatment during pandemic. Follow up study with large sample size to be included. That will allow comparison between those with predomination contamination obsessions and others. It will be useful to study if the understanding of CO VID 19 reduces the risk of worsening.</p>
</sec>
</body>
<back>
<ack>
<title>Acknowledgement:</title>
<p>None</p>
</ack>
<sec>
<title>Source of Funding:</title>
<p>This research has not received specific financial grant from any funding agency in the public, commercial or not-for-profit sectors</p>
</sec>
<sec>
<title>Conflict of Interest:</title>
<p>The authors have declared no conflict of interest with respect to the research, authorship, and/or publication of this article</p>
</sec>
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<fn-group>
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